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Xanax 2mg (Alprazolam)

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ABOUT

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Alprazolam, sold under the brand name Xanax, among others, is a short-acting tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring.[6] It is most commonly used in short-term management of anxiety disorders, specifically panic disorder or generalized anxiety disorder (GAD).[7] Other uses include the treatment of chemotherapy-induced nausea, together with other treatments.[5] GAD improvement occurs generally within a week.[8][9] Alprazolam is generally taken by mouth.[5]

Common side effects include sleepiness, depression, headaches, feeling tired, dry mouth, and memory problems.[5] Some of the sedation and tiredness may improve within a few days.[10] Due to concerns about misuse, some do not recommend alprazolam as an initial treatment for panic disorder.[11] Withdrawal or rebound symptoms may occur if use is suddenly decreased;[5] gradually decreasing the dose over weeks or months may be required.[8] Other rare risks include suicide, possibly due to loss of inhibition.[12] Alprazolam, like other benzodiazepines, acts through the GABAA receptor.[5]

Alprazolam was patented in 1971 and approved for medical use in the United States in 1981.[5][13] Alprazolam is a Schedule IV controlled substance and is a common drug of abuse.[2][14] It is available as a generic medication.[7] In 2018, it was the 37th most commonly prescribed medication in the United States, with more than 20 million prescriptions

Medical Uses

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Alprazolam is mostly used in short term management of anxiety disorderspanic disorders, and nausea due to chemotherapy.[5] Alprazolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression.[17] The FDA label advises that the physician should periodically reassess the usefulness of the drug

Panic disorder:

Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks.[18] However, it is not a first line treatment since the development of selective serotonin reuptake inhibitors. Alprazolam is no longer recommended in Australia for the treatment of panic disorder due to concerns regarding tolerance, dependence, and abuse.[11] Most evidence shows that the benefits of alprazolam in treating panic disorder last only 4 to 10 weeks. However, people with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit.[17][18]

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In the United States, alprazolam is FDA-approved for the treatment of panic disorder with or without agoraphobia.[18] Alprazolam is recommended by the World Federation of Societies of Biological Psychiatry (WFSBP) for treatment-resistant cases of panic disorder where there is no history of tolerance or dependence.[19]

Anxiety disorders:

Anxiety associated with depression is responsive to alprazolam. Clinical studies have shown that the effectiveness is limited to 4 months for anxiety disorders.[18] However, the research into antidepressant properties of alprazolam is poor and has only assessed its short-term effects against depression.[20] In one study, some long term, high-dosage users of alprazolam developed reversible depression.[21] In the US, alprazolam is FDA-approved for the management of anxiety disorders (a condition corresponding most closely to the APA Diagnostic and Statistical Manual DSM-IV-TR diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. In the UK, alprazolam is recommended for the short-term treatment (2–4 weeks) of severe acute anxiety

.

Side Effects

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Drowsiness, dizziness, increased saliva production, or change in sex drive/ability may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (such as hallucinations, thoughts of suicide), slurred speech or difficulty talking, loss of coordination, trouble walking, memory problems.

Get medical help right away if these rare but very seriousyellowing eyes or skinseizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rashitching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

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